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As for nephroprotection, an RCT on the use of febuxostat vs topiroxostat show none improvement in urinary protein/creatinine ratio
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Eating 1.2g protein per kg of body weight daily and doing resistance training 3 times a week can help improve treatment results
Since tirzepatide is administered once weekly, some patients anecdotally report that morning administration (rather than evening) may help minimize any potential sleep interference, though this has not been formally studied
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