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NICE Technology Appraisal 875 (Wegovy) and TA664 (Saxenda) recommend these treatments within specialist tier 3 or 4 weight management services for adults with a BMI of 35 kg/m or above (or 32.5 kg/m or above for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds), with weight-related comorbidities

Most GLP-1 compounds remain detectable in your body for 5 to 7 days after administration, though the therapeutic window and peak appetite-suppressing effects occur within the first 24 to 48 hours

Some people respond well

References Wilding JPH, Batterham RL, Calanna S, et al