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2.3 Oxidative Stress, Endoplasmic Reticulum, and Mitochondrial Injury In NASH patients, studies revealed a positive relationship between OS levels and IR severity, fat degeneration, inflammatory response, and fibrosis (Tariq et al., 2014)

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miR-126 mimic counteracts the increased secretion of VEGF-A induced by high glucose in ARPE-19 cells