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However, publication bias occur in nighttime symptoms, such as nasal congestion (p = 0.049) in patients with asthma and AR, changes in nighttime asthma symptoms (p = 0.0009) in patients with asthma
Excessive caffeine creates additional oxidative stress
Research on tissue distribution indicates that 45 min post-administration (oral dose 90 mg/kg), the levels of SIN in various rat tissues, ranked from highest to lowest, were detected as: kidney, liver, lung, spleen, heart, brain, and testicles (86)
Furthermore, studies have suggested that the therapeutic synergy between sitagliptin and metformin co-administration can increase mRNA and protein expression levels (Naseri et al., 2022)
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