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These effects on energy balance complement incretin-mediated appetite suppression, facilitating greater weight loss
While the most accurate way to assess gastric emptying is by nuclear scintigraphy, the use of GUS has been offered as an inexpensive and effective way to help determine RGC, yet the lack of studies using ultrasound to assess gastric emptying in patients currently on a GLP-1 RA regimen has created a gap within the literature (Oprea et al
Impairment of incretins (secretion/activity) has been described in several IR states beyond T2D, such as obesity, prediabetes, and polycystic ovary syndrome (PCOS) [34, 41, 43]
Particular attention is warranted for diverse populations, including older adults, individuals with advanced renal disease, pregnant patients, and those at risk of lean mass loss during rapid weight reduction
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