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(4) Clinical combinations: BBR-silymarin co-administration significantly improves glycemic control (fasting glucose, HOMA-IR) and lipid profiles (TG, LDL) in diabetic patients, and decreases BMI, and the WHR in obesity patients versus BBR monotherapy [196]
Even the single study that did suggest a possible link found only a handful of cases in people with diabetes, a group already at increased risk for eye disease and nerve disorders
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Similarly, studies on oxidative stress in skin conditions support the idea that antioxidants could play a beneficial role in preserving cellular integrity (Bickers & Athar, 2006)
The combination produced a mean weight reduction of 20.4% under the treatment-policy estimand, versus 3.0% with placebo (-17.3% difference
