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Description

It represents a significant shift from gut-hormone-based treatments, operating entirely within the central nervous system

A word on why once daily is the anchoring frequency rather than something more elaborate

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The compound exhibits a notably long half-life of approximately 9 days (220 hours) and is metabolized primarily by cytochrome P450 3A4 to its active metabolite M1 (NS2360), which has an even longer half-life of 16 days (374 hours)