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Curr Nutr Rep 14 , 61 (2025)
Because the satiety-signaling mechanism is highly dose-dependent at the upper end of the titration schedule, Wegovy users should especially prioritize the abdomen as their default site to ensure they are getting the full benefit of their prescribed dose
Once you reach a stable maintenance dose (typically by week 812), your tolerance for fasting often improves
The higher end of this range may not feel realistic early on, especially if your appetite is significantly reduced
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