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Approximately 25% of total weight lost on tirzepatide was lean mass (SURMOUNT-1 DXA substudy), and in semaglutide trials, that proportion may reach up to 40% (STEP 1 DXA subset)

A spokesperson for Novo Nordisk told Scientific American that prices for higher doses will be shared in the new year

Patients are advised to take it on an empty stomach with a small amount of water, waiting at least 30 minutes before eating or taking other medications

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Aim for a half hour of weight lifting or other forms of resistance training, like squats, Pilates, or using resistance bands, at least twice a week