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It has accelerated healing of transected tendons and ligaments in rats when given by several routes, improved muscle and bone-to-tendon junction recovery, and protected gut tissue in ulcer and colitis models
Bridging the Gap Between the Clinic and Everyday Life In clinical trials, patients benefit from frequent follow-ups, coaching, and structured care
The setup, per Lilly's investor disclosures and ClinicalTrials.gov: Duration: 80 weeks of treatment (the longest of any TRIUMPH trial) Population: Adults with obesity (BMI 30) or overweight (BMI 27) plus at least one weight-related comorbidity, without type 2 diabetes Doses: 4 mg, 8 mg, and 12 mg retatrutide vs matched placebo, all once-weekly subcutaneous Primary endpoints: Mean percent change in body weight
2021 Mar 9;12:2042018821997320
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