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Because serum-containing media include abundant IGFBPs that would sequester native IGF-1, DES(1-3) IGF-1's reduced IGFBP affinity ensures that the applied dose approximates the actual receptor-activating dose
Food supplements must not be used as a substitute for a balanced and varied diet
Similarly, CJC-1295 selectively activates GH
Hypothalamic Pathway The hypothalamus regulates GHRH and somatostatin secretion, which determine the timing of GH pulses
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