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These include localised or systemic infections from non-sterile manufacturing, severe toxicity from chemical contaminants, unpredictable side effects from incorrect dosing, and rapid drug degradation caused by a total lack of temperature-controlled shipping and storage

In their separate trials, retatrutides top dose produced a higher average weight loss (28.3%) than Mounjaros (22.5% in SURMOUNT-1), a difference of roughly 6 percentage points

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It may lead to muscle breakdown or joint pain

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