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Additionally, activated GPER can upregulate glucose transporters (GLUTs) and hexokinase (HK), increasing the level of aerobic glycolysis and leading to the accumulation of metabolic waste products, including lactic acid, which helps tumor cells evade immune surveillance and enhances their invasive capabilities [6, 34]
(101(2)):297-317 doi:10.1016/j.mcna.2016.09.013
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NGF primarily supports small-fiber sensory neurons, the exact neurons damaged in the most common forms of neuropathy
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