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No chronic toxicity has been documented in animal research (Vukojevic et al., 2020)
In one study, approximately one in every three people with depression had elevated homocysteine levels
Function approaches baseline
The lack of adequate cobalamin in the body hinders the regeneration of tetrahydrofolate, which eventually leads to megaloblastic anemia due to the functional folate deficiency.[9][10] On the other hand, the methylmalonyl-CoA mutase helps to metabolize odd chain fatty acids and branch chain amino acids.[5] Cobalamin is also thought to keep the bodys level of sulfhydryl (SH) groups in reduced form
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