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Adv Drug Deliv Rev 61(15):14121426
[70] found in vivo and in vitro studies that GLP-1 and its analog exendin-4 were able to induce an increase in ABCA1 mRNA, increase the expression of apo AI mRNA and promoter, thereby increasing apo AI secretion, indicating that GLP-1 in hepatocytes may mediate the outflow of intracellular cholesterol to apo AI through the ABCA1 pathway
Targeting 6-thioguanine to the kidney with S -(guanin-6-yl)- L -cysteine
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