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Finally, In a recent meta-analysis on 56,004 patients from 7 CVOTs (68.9% patients with established cardiovascular disease), GLP-1RAs reduced the risk of MACE by 13%, of cardiovascular death by 12%, of all-cause mortality by 11%, of non-fatal stroke by 16%, of hospitalization for heart failure by 9%, of macroalbuminuria by 24% [13]
[6] [7] Domperidone has restrictions due to cardiac risks and should be avoided in certain patients with heart conditions or those taking medications that affect heart rhythm
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This offers the potential for further improvements in health outcomes and possibly greater weight loss, especially for those who may require higher effectiveness
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