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Nutritional authorities often establish the recommended nutrient levels on supplement labels based on what it takes to avoid deficiency
Unfortunately, I have found people with Hashimotos may have impairments in their bodys ability to synthesize carnitine due to: Multiple nutrient deficiencies (beyond carnitine) : Other cofactors (additional nutrients needed to support our body in making carnitine) can also be lacking in those with Hashimotos, including having adequate amounts of iron ( iron deficiency with or without anemia is a common issue for people with Hashimotos, and it is thought that low iron may contribute to the low levels of carnitine found in most pregnant women), vitamin B3 (niacin), vitamin B6, and vitamin C
Failure to achieve any biomarker shift after 12 weeks of full protocol indicates either non-adherence, ongoing exposure, or that GSH depletion is downstream rather than primary at which point the differential outlined in the next section becomes essential
Studies have shown that PPIs can increase the uptake of cisplatin cells in an acid-dependent manner and enhance the role of cytotoxic agents in chemotherapy-resistant epithelial ovarian cancer [89, 132]