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In 2019, a proof of concept, phase IIa open label study in Germany aimed to evaluate the safety and efficacy of melanotan I implants in patients with XP [12]

Mico JA, Rojas-Corrales MO, Gibert-Rahola J, Parellada M, Moreno D, Fraguas D et al

The TGA described the eye disorder, non-arteritic anterior ischaemic optic neuropathy (NAION), as a rare but serious condition that may result in permanent visual impairment, including blindness and no treatment has been shown to improve visual acuity outcomes

Do not use the pen if it has been frozen or if the solution appears cloudy, discolored, or contains particles