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As a retrospective database study, it is difficult to ascertain why this study found that patients were more likely discontinue weekly therapy at 24 months as this seems inconsistent with previous findings

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The exact temperature limit (typically 25C or 30C) and allowable duration vary by product, so check your specific product leaflet or SmPC

To adjust for potential confounding, we used inverse probability of treatment weighting (IPTW) based on propensity scores, a method that allows balancing without losing generalisability [17]

It also cut the risk of developing diabetes by 73% and the risk of non-fatal stroke by 7%