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Zepbound targets two hormone receptors (GLP-1 and GIP), while Wegovy targets one
The key insight is that tirzepatide is not a medication where more always means better
In animal studies, as well, GLP-1 analog administration induced GnRH neuron release via modulation of nitric-oxide and endocannabinoid pathways that regulate the GABAergic current in the postsynaptic GnRH neurons (12)
#GLP1 #Pharma #Biotech #HealthcareStrategy #Obesity #Diabetes #DrugPricing Link to this week's report: Thank you for a strong overview, AnneSophie
Ozempic is FDA-approved only for type 2 diabetes
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