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The FDA, recently approved Baxdrostat (Baxfendy), developed by AstraZeneca - the world's first aldosterone synthase inhibitor (ASI) - for adults with hypertension that remains uncontrolled despite multiple antihypertensive medications
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Portion control is essential: patients often find 12 cups manageable, whereas pre-treatment portions (35 cups or more) become uncomfortable
In the treatment group, semaglutide dosing was increased monthly until they reached 2.4 mg, or to the dose that was tolerated without adverse side effects
Semaglutide works by mimicking the action of the natural incretin hormone glucagon-like peptide-1 (GLP-1), which is responsible for regulating blood sugar levels [2]
Slowing the rate at which the stomach empties changes the timing and volume of what reaches the small intestine, and the downstream gut has to accommodate that altered delivery pattern
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