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The EXSCEL trial (Bethel et al., 2020) and LEADER trial (Marso et al., 2016) investigated the effect of exenatide and liraglutide, respectively, on microvascular and cardiovascular outcomes in patients with type 2 diabetes
GLP-1 receptor agonists are synthetic analogs or modified versions of this endogenous hormone, designed to resist degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), thereby extending their duration of action from minutes to hours or days
The oral GLP-1 market size in 2025 was US$ 6.81 billion, expected to grow to US$ 9.19 billion in 2026 and further to US$ 137.36 billion by 2035, backed by a robust CAGR of 35.05% between 2026 and 2035
Zhai, S., Liu, C., Vimalraj, S., Subramanian, R., Abullais, S
If someone says sermorelin melted fat in a few weeks, ask what else changed
