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Tesamorelin is a stabilised GHRH analog engaging the GHRH receptor

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Additional elements of the expression cassette included an FMDV IRES upstream of P1, the FMDV 3UTR downstream of 3CD followed by a 20 nucleotide long polyA tail, as well as the T7 promoter and terminator elements 15

(PubMed) Gao X, Wilde PE, Lichtenstein AH, Bermudez OI, Tucker KL

The Journal of Endocrinology, 2017 May;233(2):R67-R79