A 5mg target dose would deliver approximately 3.9mg
Additionally, GLP-1 analogs reduced energy expenditure, with only tirzepatide showing a significant decrease in the respiratory quotient (RQ) in MC4R KO mice
I currently take Zepbound to help aid in weight loss
In addition, since GLP-1 is also produced locally within pancreatic islets, and its expression increases with the progress of diabetes development 22,23,24,25,26,27 , linagliptin may exert insulinotropic and glucagonostatic effects directly on the islets by elevating local GLP-1 concentrations
Though the weight isnt falling off like water from a Ducks back, I am down 10 lbs over the first 3 weeks, and am motivated by the progress