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DIO ovariectomized female mice treated chronically with a stable estrogen/GLP-1 coagonist had significantly greater body weight and fat mass loss as compared to GLP-1R monagonists
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If you freeze something, the structure of the peptides changes because ice crystals form
Yu et al., 2012)
Participants in the profile characterized by high GLP-1 and high GIP tertiles achieved low response to both drugs
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