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Clinical data also showed that low CPT1A and PPAR correlated with poor prognosis (114, 123)
Ozen OA, Cosar M, Sahin O, et al
Oral GLP-1 therapies emerged as game-changers: Rybelsus (oral semaglutide) was approved for diabetes in 2019, and in December 2025 the FDA approved Wegovys first oral pill (25 mg semaglutide) for obesity ( [35] )
GLP-1 RAs offer multiple beneficial effects and have a favorable safety profile
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