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The clinical model was trained on the IML1 and SABR cohorts and externally validated on the PANDORE cohort, achieving a 12-month AUC of 80.8% (95% CI 60.8100.8) in the validation cohort (Extended Data Fig
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It led to decreased screening for disordered eating histories while completely ignoring the physical consequences of unmonitored rapid weight loss, such as the loss of healthy muscle mass
Patients should maintain open communication with their healthcare providers about any persistent side effects, as dose adjustments might be necessary
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