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median TTAF of 2 weeks) indicates more friction than peers
Bakalov D, Sabit Z, Tafradjiiska-Hadjiolova R
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Furthermore, in ECL1 of GCGR there are two glycine residues (G207 ECL1 , G219 ECL1 ) that disconnect the helical structure in the active state, whereas the G219 ECL1 is not conserved in GLP-1R and the helical conformation is relatively intact in this region of GLP-1R
Second, dosing protocols in the community are all over the place
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