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However, clinical studies with liraglutide have shown that this effect is generally modest and does not significantly impact the efficacy of most medications tested, including paracetamol and oral contraceptives
A rapid increase in the dose may cause more side effects, including back pain
Motivation and commitment: GLP-1 therapy requires a strong commitment, including regular injections and lifestyle modifications to lose weight and keep it off
Some researchers have hypothesized that GLP-1 receptor stimulation might promote pancreatic duct cell proliferation or increase pancreatic enzyme secretion, but animal studies have not consistently demonstrated these effects at therapeutic doses
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