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Liraglutide also decreased angiotensin II-induced oxidative stress by increasing the levels of NADPH oxidase activity, increasing endothelial NO availability, and reducing immune cell infiltration by reducing the levels of F4/80 (a macrophage marker F4/80 with proinflammatory properties) expression in cardiac tissue thus reducing the overall level of oxidative stress in hypertensive heart disease

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doi: 10.1161/CIRCHEARTFAILURE.113.000672 222 KimDJeongWKimYLeeJChoSWOhCMet al

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