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The synthesis of GSH is non-redundantly controlled by the glutamate-cysteine ligase catalytic subunit (GCLC)
Like the role of chronic alcohol consumption and an associated poor diet leading to thiamine deficiency, alcoholism is the leading cause of deficiency in B6
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Activating the HGF/c-Met signaling pathway initiates a cascade of events that: Stimulates synaptogenesis the physical formation of new synaptic connections between neurons Promotes dendritic spine formation the small protrusions on neurons essential for receiving signals Enhances synaptic density in brain regions associated with learning and memory Supports neural stem cell activity and neuroplasticity Reduces neuroinflammatory signaling, offering a neuroprotective effect Structural vs
Commun., 12 : 3985
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