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The injection can be given every 6 months if due to a dietary deficiency, or 2-3 months if the cause of your low B12 levels is pernicious anaemia

doi: 10.3390/diagnostics14080848

But the results from animal models are consistent enough that many integrative vets have started using it off-label, and anecdotal reports from dog owners are stacking up

8 ounces of malt liquor at 7% alcohol