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Dai C, Xiao X, Li D, Tun S, Wang Y, Velkov T, Tang S (2018) Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis
Recently, abnormalities in neuroendocrine function have been suspected to be responsible for impaired patient energy and mood
3.1.9 Epigallocatechin-3-gallate (EGCG) and epicatechin EGCG, a polyphenol abundant in green tea extract, is a STAT1 inhibitor.EGCG prevents cisplatin cytotoxicity through anti-apoptotic and antioxidant effects ( in vitro and ex vivo (Xie et al., 2004).EGCG acts through phosphatidylinositol 3-kinase (PI3K)/Akt signalling in cochlear NSCs to promote cell growth and neuronal differentiation, which can be used for the treatment of hearing loss (Zhang et al., 2016), and has an important protective mechanism against cochlear oxidative damage
It is a synthetic pentadecapeptide, a chain of 15 amino acids, derived from a protective protein found naturally in human gastric juice