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The complex travels through the small intestine until it reaches the terminal ileum, where specialised receptors called cubam (a complex of cubilin and amnionless proteins) recognise and facilitate the uptake of the B12-IF complex into enterocytes (intestinal cells)
Not intended to diagnose, treat, cure, or prevent any disease.
Other more complex models include dynamic BBB models and microfluidic models/3D chip-style models
(2013) Meta-analysis of methylcobalamin alone and in combination with lipoic acid in patients with diabetic peripheral neuropathy
Mol Ther Nucleic Acids (2020) 19:46881
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