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The peptide works as a dual agonist, meaning it activates two different receptors simultaneously

The SURMOUNT trials demonstrated up to 22.5% mean weight loss at the highest dose

Meanwhile, average annual treatment costs for oncology and rare diseases [are] both approaching $300,000 per patient. A SEQUEL TO BIG PHARMAS PRICE-GOUGING ON DIABETES DRUGS GLP-1s grew out of a category of medicines originally designed for treating diabetes

Some investigators have proposed that GLP-1RAs improve myocardial insulin sensitivity, enhance glucose oxidation rates, reduce fatty acid oxidation, and thereby optimize myocardial energy metabolism, ultimately improving cardiac function