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Until higher-quality data emerge, clinicians should counsel patients with curiosity, caution, and clinical judgment while continuing evidence-based skin care

This procedure occasionally interferes with the blood sugar levels and results in low blood sugar commonly referred to as hypoglycemia

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Patients report faster pigmentation correction, more even tone, and a general quality that they describe as their skin looking more like it did years earlier

Gut microbiome composition represents another potentially important variable, though its specific role in allulose metabolism requires further investigation