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Blood test markers to discuss with a clinician Marker A1c Why it matters Shows longer-term glucose control before and during incretin-pathway protocols
Finerenone Finerenone is a non-steroidal mineralocorticoid receptor antagonist (contrast with spironolactone, a steroidal mineralocorticoid RA) that has been shown to reduce the risk of CKD progression (Bakris et al, 2020) and improve CV outcomes (Pitt et al, 2022) compared to placebo in randomised controlled trials in subjects with type 2 diabetes and albuminuric CKD
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Suttorp, N., Toepfer, W., Roka, L., 1986
This damage impairs the metabolic adaptability required for CD4 + T cells to differentiate into Tregs, forcing a shift toward the Th17 phenotype (78) and contributing to Treg functional exhaustion
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