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through the ectopic pore, it enters the translocase of inner mitochondria membrane 23 (TIM23) complex in the mitochondrial inner membrane, and once it has crossed the mitochondrial inner membrane, it is segmented by mitochondrial processing peptidase (MPP) and presenilin-associated rhomboid protein (PARL) and then degraded [28,29,30]

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A large retrospective study found a two-fold increased risk of anxiety and suicidal behavior and a three-fold increased risk of major depression among GLP-1RA users

b) Adjust the concentration of SSA in the sample solution to 0.5-1% with ddH 2 O before the assay

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