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Presented for research literature review only Gabery S et al
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Worked examples Example 1: 5 mg/mL vial 0.5 mL x 5 mg/mL = 2.5 mg Example 2: 3 mg/mL vial 0.5 mL x 3 mg/mL = 1.5 mg Example 3: 2.5 mg/mL vial 0.5 mL x 2.5 mg/mL = 1.25 mg Example 4: 2 mg/mL vial 0.5 mL x 2 mg/mL = 1.0 mg If your concentration does not match any of these common values, just plug your number into the formula
We assessed cytochrome P450 3A4 (CYP3A4) activity in the derived smHLCs (under all conditions), by analysing the ability of the cells to induce CYP3A4 upon challenge with the proto-typical inducer Rifampicin
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