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KEY TAKEAWAYS Insulin resistance can be tested through fasting insulin and glucose ratios, even in countries where insulin testing is less common Rapid weight loss rates above 15% annually may indicate no need for dose increases Severe GI side effects warrant investigation beyond medication adjustment, including gallbladder evaluation DEXA scans provide valuable visceral fat measurements, but results should be interpreted alongside overall health markers Maintenance strategies should focus on nutritional stability before considering medication tapering NOTABLE QUOTE "It's not that the medicine causes the rebound weight gain, it's that with the medication in there, the body is getting better signals, and then you go and take the medication away and you're in the same boat." Dr
However, increasing its quantity through quality supplementation can have multiple benefits
Because semaglutide stays in the body about a week, women planning a pregnancy should stop it at least 2 months ahead and use contraception while taking it
The same goes for those experiencing excessive or persistent rectal bleeding and conditions like anal stenosis, anal stricture, or scar tissue formation