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Soleimanzadeh A, Mohammadnejad L, Ahmadi A
Background Almost half of adults worldwide now live with excess body fat, a figure projected to climb to 54% by 2035, and it drives type 2 diabetes, hypertension, dyslipidemia, osteoarthritis, and mood disorders
Significant improvements in beta-cell activity are indicated by HOMA2-B percent change from baseline increases ranging from 93 to 163% for tirzepatide (5, 10, and 15 mg doses), outperforming dulaglutide and placebo effects
Anabolic steroid induced hypogonadism studied with hCG [PMID: 9538490] Laboratory literature summary: Anabolic steroid induced hypogonadism studied with hCG
The dose-response data supports targeting specific outcomes
