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Supplementing it has shown real effects on skin quality, hair thickness, wound healing, and overall tissue repair
From a pharmacological safety perspective, the adverse effect profile of retatrutide based on Phase 1 and Phase 2 clinical trial data (including the NEJM 2023 Phase 2 trial) includes: Gastrointestinal effects: Nausea, vomiting, diarrhoea, and constipation (the most commonly reported side effects in trial participants) Injection site reactions: Redness, swelling, or discomfort at the injection site Cardiovascular effects: Increases in heart rate have been observed in trial participants [21] [22] Hypoglycaemia: Particularly relevant in individuals with diabetes or those taking insulin, sulfonylureas, or other glucose-lowering agents Potential thyroid effects: GLP-1 receptor agonists have been associated with thyroid C-cell changes in rodent studies
Thinking of skipping sunscreen the next day
More practically, if you are taking vitamin C supplements with capsules on an empty stomach, the gastric pH reduction is not the concern (stomach is already acidic)
Yet the documented downstream effects on repair, inflammation, and vascular signalling continue for weeks beyond the last dose
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