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Oral ingestion of HC increases the levels of collagen-derived peptides in the blood torrent and improves the skin properties such as elasticity, skin moisture, and transepidermal water loss
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54 The observation that deficiency of Puma (or combined deficiency of Puma and Noxa or Puma and p21) promoted the development of C-myc-driven lymphoma, 107,108 which suggested that p53-mediated apoptosis could exert obvious tumor-suppressive effects
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