The Wegovy pill (OASIS 4 trial) enrolled 307 adults living with obesity, or with excess weight plus a weight-related condition, and without type 2 diabetes
The approval of orforglipron signals both a shift toward more accessible obesity treatments and a test case for the FDAs new accelerated review pathway
However, given the ubiquity of ER stress-related pathways and IR crosstalk mentioned above, diabetes-related IR is likely to be involved in the generation of ER stress in PD
However, the manufacturer clearly states that Jardiance is not made to lower body weight, even though weight loss can occur as a secondary effect
Chia pudding made with chia seeds, soy milk, fruit, and a little maple syrup (make ahead and let this sit in the refrigerator overnight)