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Knockdown of LONP1 increases mitochondrial TDP-43 levels, exacerbating mitochondrial damage and neuronal degeneration, whereas overexpression of LONP1 effectively blocks TDP-43-induced pathological effects

Approximately 30% of the total protein in the myelin sheath consists of MBP, which is dependent on methylation

All mice were inoculated with control cells in one flank and GCLC -silenced cells in the opposite flank

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