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Therefore, experimental findings do not support the theory of intrinsic hypercoagulability of sclerosing solutions as the mechanism of action for thrombus formation during sclerotherapy (see Chapter 1)
Repeated freeze-thaw cycles can denature and reduce solubility
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Add physical activity most days of the week
In a phase 2 trial, once-weekly cagrilintide produced dose-dependent weight reductions in people with overweight or obesity, which is what moved the amylin pathway into serious combination development ( Lau et al., Lancet 2021 )
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