In the ischemia/reperfusion-induced fibrosis C57BL/6J mouse model, transcriptomic and metabolomic analyses showed that dapagliflozin treatment mitigated accumulation of tricarboxylic acid (TCA) circulating metabolites and up-regulation of inflammation in fibrotic renal cortical tissue
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To view or add a comment, sign in , Novo Nordisk has entered into a definitive agreement to acquire Akero Therapeutics for USD 4.7 billion in cash, with an additional contingent value right (CVR) of up to USD 0.5 billion tied to future regulatory approval of efruxifermin (EFX)
One is Virta Health, which advertises its nutrition-focused weight management program as a proven approach for deprescribing GLP-1s when clinically appropriate. A Virta-funded study assessed 154 people with Type 2 diabetes who stopped using GLP-1 medications but continued following Virtas program, concluding that their weight did not significantly increase after a year