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Some people experience it only during the first few weeks, while others may deal with mild discomfort for longer
Quick Answer: No single GLP-1 receptor agonist is definitively easiest on the stomach, but dulaglutide and liraglutide may cause slightly fewer gastrointestinal side effects than higher-dose semaglutide or tirzepatide, though individual tolerance varies considerably
Because sublingual tirzepatide is still under investigation, its safety profile via this route is not yet fully established
Acknowledgements The authors would like to acknowledge Dr
Both should be considered essential
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