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In line with these results, in the randomised, placebo-controlled SUSTAIN 5 trial of once-weekly subcutaneous semaglutide as an add-on to basal insulin, the insulin dose was significantly decreased from baseline with both the semaglutide 0.5 and 1.0 mg doses compared with placebo [38]

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Approximately 58% of patients using GLP-1 drugs report significant weight reduction benefits, which has accelerated the GLP-1 Drug Market penetration across obesity treatment segments

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