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If done too early, there can also be overlap of doses which may increase potential for side effects if the prior round hasnt fully worn off yet
The key difference is that the quarterly plan requires a longer commitment but provides a lower monthly rate
You'll see this as precipitate when the vial thaws
NICE guidance advises testing people who have at least one risk factor, such as long-term metformin use, together with at least one symptom or sign
This is called tapering your dose
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